Gout is caused by excess urate (or uric acid) in the blood. When this happens, tiny crystals can form and collect in one or more joints causing inflammation and pain (gout).2 If urate crystals enter a joint, they may trigger the development of inflammation.1 The affected joint becomes red, swollen and extremely painful and tender.1
In most patients, only one joint is affected, and the big toe is affected first in 70% of cases.1 However, in 10% of patients more than one joint is affected. 1
Gout is usually diagnosed on the basis of its distinctive symptoms and an examination of the joint.1 An untreated attack generally lasts for a few days, then dies down and the joint gradually returns to normal.1
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