RA varies from person to person in the way it affects an individuals joints.4 Some people have little or no damage to joints, or suffer only very minor involvement in a few joints.4 Predominantly, RA affects peripheral joints, usually beginning in the small joints of the hands and feet, spreading later to the larger joints.5
The joints most frequently affected by RA include the knuckles and middle joints of fingers, wrists, shoulders, middle joints of toes, balls of the feet, ankles and knees.4 Joints which are affected less frequently are the elbows, hips and neck.4
In addition, RA can affect the tendons and, in some people, can also cause inflammation of the lungs and blood vessels.5 Some people with RA feel generally ill, with overwhelming tiredness or fatigue, which may be as difficult to cope with as the painful joints.4
RA symptoms tend to come and go with no particular patterns, with patients experiencing ‘flare-ups’ when the joints become more inflamed and painful, with months or years in between when there is little apparent inflammation.4
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